3D (Dimensional) microtissues are commonly used in regenerative medicine, medicine design, toxicology studies and advance cancer research. Microtissues which are constructed by this technique mimic natural in vivo condition and it stands for shifting form between in vitro studies and in vivo research. Scaffold-free microtissues produce own extracellular matrix and cells proliferate faster. However microtissue is used in vitro experiments, they mimic in vivo condition by producing own matrix.
Recently, RGD peptides which are commonly used biomaterials consist of GRGDS sequences and it has acti ...Daha fazlası
The main purpose of my thesis is to develop a Swarm Robotics Platform which will
use Cellular Automata Glider model and generate itself with “Game of Life” rules.
The method was experimentally tested with autonomous mobile robots and real-time
PC based simulation software, in all cases very good paths were obtained with
negligible processing effort, and low cost production. Presented results indicate that
the Cellular Automata approach is a very promising method for real time path planning
and Glider like robotic swarms can be used for self-replicating and moving swarm
robots.
We desig ...Daha fazlası
Within the scope of the thesis study, interpolation methods used for evaluating spatially varying data and for presenting the information obtained from the data via maps were investigated. A method for generating an open source web based interpolation map for the most commonly used interpolation methods is presented. Today, many commercial Geographic Information Systems (GIS) software are used in the production of interpolation maps. However, this situation causes the users to pay a large amount of money or use cracked programs. Although there are open source softwares, which can create interp ...Daha fazlası
THE EFFECT OF PULSED ELECTROMAGNETIC FIELDS FOR IN VITRO WOUND HEALING EXPOSURE SYSTEMS
SUMMARY
Electromagnetic fields have achieved important role as stimulator and therapeutic facility in biology and medicine (Blank & Findl, 2013). The effects of low magnitude, low frequency pulsed electromagnetic fields have been a period of study since past few decades, which was mainly on the treating soft tissue injuries, skin ulcers, nonuniform bone fractures and degenerative nerve healing (Hug & Röösli, 2012b). Chronic wounds are a major healthcare problem for patient morbidity and contribute signi ...Daha fazlası
Özet:İnsansız Hava Araçları (İHA) genellikle pervane tahrikli ve düşük hızlı uygulamalara yöneliktir. Mikro turbojet motorları ise çok daha yüksek yakıt tüketimine bağlı olarak daha kısa menzillere sahiptir. Fiyat ve karmaşıklık sorunları nedeniyle, turbofanlar yerine turbojetlerin kullanımı kısıtlanmaktadır. Bununla başa çıkabilmek için, temel bir mikro turbojet, ek (booster) kompresörü ve düşük basınçlı türbin bileşenleri olmadan tek milli turbofana dönüştürülebilir. Bu normalde eşleştirme sorunlarına neden olur çünkü fan hızını bağımsız olarak ayarlamak için iki mil gerekir. Daha basit bir ...Daha fazlası
ÖZETBu tezde, iki farklı varaktör diyot tabanlı, elektronik olarak kontrol edilebilen, DC öngerilim kontrol devrelerine sahip düzlemsel yönlü kuplörler sunulmuştur. Varaktör diyotların ters öngerilim gerilimlerinin büyüklük değerleri, mobil uygulama ile Bluetooth kablosuz iletişim üzerinden tek bir mikrodenetleyici üzerinden kontrol edilmiştir. Önerilen akıllı yönlü kuplörün çalışma frekansına ayarlanması için herhangi bir bağlantı oranı, DC kutuplamalı ağda uygulanacak doğru voltajın belirlenmesi için deneysel veriler makine öğrenme algoritmasında eğitilerek geniş çapta ayarlanabilir. Önerile ...Daha fazlası
ABSTRACTOsteomyelitis is a disease in which the process of bone destruction and loss is caused by microorganisms. Osteomyelitis has an increasing incidence rate that could cause chronic and acute infections. Bone infection has caused recurrent and permanent damage in 40 of the patients. 2-5 of infections caused by medical devices used in orthopedic surgical operations are osteomyelitis. More than half of osteomyelitis cases are caused by gram-positive bacteria such as Staphylococcus aureus and Staphylococcus epidermidis. In order to prevent the occurance of osteomyelitis due to the medical dev ...Daha fazlası
Fouling is the accumulation of undesired particles on heat transfer surfaces which affects the heat transfer performance of a heat exchanger negatively. The accumulation of these particles prevents heat from being transformed through the heat exchangers by generating a fouling layer-like insulation. The main aim of the thesis is to investigate the machine learning algorithms to classify and predict the fouling status of PHE used in combi-boilers, to generate the background of the predictive maintenance, besides investigating the fouling effect on PHEs in terms of heat transfer and energy consu ...Daha fazlası
Within the scope of this thesis, PLA-based composites have been developed and coated with peptide to increase biocompatibility for temporary implant applications and PLA biocomposite materials have been produced. HA and β-TCP were used as additive materials, and PLLA and PDLA polymers were used as polymer matrix. The main purpose is to obtain the composite with the best mechanical properties and to improve the biocompatibility properties as a result of coating this final material with peptide. In the first stage, 10% HA (PLA-10 HA), 10% β-TCP (PLA-10TCP) and 5% HA + 5% β-TCP (PLA-5TCP-5HA) are ...Daha fazlası
Plasma is an ionized gas generated under an electric field that contains photons, free electrons, ions, free radicals, and reactive oxygen/nitrogen species (RONS). Cold atmospheric plasma (CAP) is generated in the cold form under a high electric field at atmospheric pressure. CAP is generated using two methods, Dielectric Barrier Discharge (DBD) and plasma jet. In the DBD method, the electrode configuration, shape, material, and substance from which the dielectric barrier is made are important. Beyond the electrode design and geometry, the barrier and electrode materials can also impact the re ...Daha fazlası
Excessive use of global energy sources causes negative environmental impacts and a reduction in the available energy resources. Therefore, energy efficiency is the main scope of engineering studies. Since household refrigeration accounts for a large portion of the energy consumption rate in buildings, several innovative techniques have been developed to improve the energy efficiency of vapor compression refrigeration systems. Suction line heat exchangers are considered one of these techniques and they are used to avoid the presence of liquid at the compressor and to prevent sweating on the suc ...Daha fazlası
Bu çalışmada, farklı zeminler ve geomembranlar (GM) arasındaki arayüzleri
etkileyen mühendislik parametreleri, kür sıvısı, kür süresi ve normal gerilme sınıfı
gibi çeşitli koşullar altında incelenmiştir. Ayrıca depolama sahaları gibi birden çok
geosentetiğin (GS) bir arada kullanıldığı tasarımlarda, GS’ler arasında oluşan
arayüzeylerde de potansiyel kayma yüzeyleri oluşabilir. Bu nedenle, bu çalışmada
aynı zamanda GM ve geotekstiller arasındaki arayüzeyler de araştırılmıştır. İlk
aşamada, GS’lerin ve zeminlerin mühendislik parametreleri laboratuvar deneyleri ile
belirlenmiştir. İkinci a ...Daha fazlası
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.