Antitumor effect of RGD peptite on cancer microtissues RGD peptidin kanser mikrodokuları üzerinde antitümör etkisi

Aydın, Veli Kaan

ABSTRACTCancer studies continue to gain interest in the recent period. Many types of cancer,especially breast cancer, continue to cause deaths worldwide and the number of people suffering from this disease is increasing. The methods that are used most at the basis of cancer studies are starting with 2-Dimensional (2D) cell culture. However, 2D cell culture can no longer adequately reflect in vivo conditions. Scientists have turned their efforts towards these 3-Dimensional (3D) cell cultures. There are many different ways of obtaining 3D cell culture. The preferred 3DPetriDish ™ technique in th ...Daha fazlası

Investigation of changes in the formation and types of non-metallic inclusions in the steel production process Çelik üretim sürecinde oluşan metal olmayan kalıntıların oluşumu ve değişimlerinin incelenmesi

Bakar, İbrahim

ABSTRACTIt is not possible to produce steel without inclusions as the process for steel production requires. Based on this fact, the researches on clean steel are concentrated on the reduction of inclusions and transformation of inclusions into harmless state by modification. The definition of steel cleanness is related to final product application. Non-metallic inclusion, in the liquid steel, causing many problems and production lost in steel production process and final application. Aluminum killed steels mostly contain Al2O3 and MnS inclusions. Al2O3 inclusions are formed during de-oxidatio ...Daha fazlası

Manufacturing and characterization of thermal conductive polymeric composite materials Termal iletken polimerik kompozit malzemelerin üretilmesi ve karekterizasyonu

Kaya, Nusret

ABSTRACTElectronic industry is growing dramatically in the last quarter of the century. Recent advances in electronics industry enable the miniaturization of micro transistors and the integration of more transistors into the electronic devices, resulting in a higher performance device. However, this condition increases the heat flow in the electronic devices. The performance of electronic devices depend on the working temperature, for this reason, it is important to remove the heat produced in the device as fast and efficiently as possible in order to hold the system temperature of the electro ...Daha fazlası

Modeling and experimental study of turbulent newtonian fluid in fully eccentric annulus considering temperature and pipe rotation effects

In this work, the effect of temperature on the pressure loss of Newtonian fluid in a fully eccentric annulus with pipe rotation is investigated. For this purpose, initially comprehensive experimental study has been conducted at Izmir Katip Celebi University (IKCU), Fluid Mechanics and Hydraulics Laboratory of Civil Engineering Department. Effect of temperature has been observed for flow velocities from 0.7 m/s to 3.4 m/s, for pipe rotations from 0 rpm to 120 rpm, and for temperatures is from 20 °C to 65 °C. The pressure loss within the test section is recorded. An increase in the liquid temper ...Daha fazlası

Design and development of a collimator mechanism that will be utilized in radiation therapy

Yazıcı, Mustafa Volkan

This thesis focuses on a Multileaf Collimator design that can shape the beam contour to fit the shape of target geometry and its design improvements. Main purpose of this design is lowering the number of leaves on the multileaf collimator and making the system easier to be controlled. As the Collimator devices undertake the most important point of the beam shaping procedure, ease of control and precision of collimator devices are the major points of operation. As the radiation therapy is one of the most complex and vital medical operations, this thesis started with the deep literature survey ...Daha fazlası

Development of microstructural and mechanical properties of aluminum alloys by equal channel angular pressing (ECAP) process Eş kanal açılı presleme (EKAP) yöntemiyle aluminyum alaşımlarının mikroyapı ve mekanik özelliklerinin geliştirilmesi

Yeşil, Mehmet Mahsun

ABSTRACTSevere Plastic Deformation (SPD), applying extreme force to alterate and refine the structures of materials permanently, have a huge potential to improve the mechanical and structural properties of materials superiously. ECAP is a kind of SPD techniques to produce submicron or nano sized grains in the material structure by applying stress to the sample passing through two angular intersected channels have the same diameters. ECAP has recently been becoming one of the most favourable candidate method in the production of nanostructured materials.One of the main objectives of this study ...Daha fazlası

Nanocomposites with graphene

The carbon fiber used in the manufacturing of advanced composites has various applications in the automotive, aerospace, and electronics industry because of their comprehensive properties such as lightweight, flexibility, high strength to weight ratio, excellent chemical resistance, superior electrical conductivity and thermal conductivity. Different kinds of carbon fiber precursors have been used and polyacrylonitrile (PAN) is the mostly utilized polymer type which is a petroleum-based, expensive and unsustainable. Remarkably, lignin is a highly accessible, low-cost, and renewable resource. ...Daha fazlası

Development of 3D-Printed plastic based low-cost sensing systems 3D baskılı plastik bazlı düşük maliyetli algılama sistemlerinin geliştirilmesi

Bayram, Abdullah

ABSTRACTEnvironment and health is two important things that are so important to human lifebecause they cannot be separated from each other. The problems related with thesetwo events will negatively affect human life. Therefore, health and environmentalproblems should be monitored with proper testing devices and analyzed. In order toperform these tests, we need cheap, reliable and fast test equipment. With therevolution of three-dimensional (3D) printing technology that is cheap, practical, fastmethod of production, this kind of test devices can be produced. This productionmethod is used to pro ...Daha fazlası

Design and development of the composite hydrogen storage tanks by using stochastic optimization methods Yüksek basınçlı kompozit hidrojen depolama tanklarının stokastik optimizasyon yöntemleri kullanılarak tasarlanması ve geliştirilmesi

Ozan Ayakdaş

ABSTRACTIn this thesis, there are five main objectives: (i) To calculate stress and strain components based on CLPT for only composite (Type IV and Type V) and aluminum-composite (Type III) pressure vessels (ii) To determine the burst pressure based on Classical Laminated Plate Theory and first ply failure theories for the cylindrical part of the Type III and Type V composite pressure vessels (iii) to compare the analytically calculated burst pressure values with the experimental and Finite Element Methods results in the literature (iv) to propose optimum stacking sequences designs for Type II ...Daha fazlası

Design and implementation of chaotic delta robot mixer system for preparing graphene nanocomposite coating Grafen nanokompozit kaplama hazırlanması için kaotik sistem tabanlı gürbüz delta robot sıvı karıştırıcı tasarımı ve gerçeklemesi

Kavur, Ali Emre

ABSTRACTThis thesis includes design, implementation and polymer nanocomposite mixing application of chaotic system based robust delta robot. Blending fluids is a vital process while preparing coating materials. The most commonly used the coating materials are polymeric materials which need to be blended in non-Newtonian fluids. This process is very critical and harder to achieve a perfectly prepared coating material.To achieve superior blending performance, two different and independent chaotic systems were used to chaotify delta robot-based blender system. One of them was used for chaotificat ...Daha fazlası