Development and Characterization of Peptide Modified Bioactive Membrane for Regeneration of Corneal Endothelial Tissue

Gülşah Sunal

Because of the drawbacks related with the current corneal transplantation techniques such as donor shortage, rejection or disease transmission risk, there is still an urgent requirement in order to produce new treatments for regenerating corneal tissue. Specially, it is also necessary to overcome the problems related with the blindness and vision losses originating from damage to corneal endothelium. By considering these, corneal tissue engineering might possess an encouraging potential to ensure alternative and innovative approaches toward the development of effective corneal tissue equivalen ...Daha fazlası

Yüksek Lisans 2023 Ozan KARAMAN İzmir Katip Çelebi Üniversitesi Fen Bilimleri Enstitüsü 2 Görüntülenme

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Development, production and characterization of ceramic based 3D tissue scaffolds = Seramik tabanlı 3B doku iskelelerinin geliştirilip, üretilmesi ve karakterizasyonu

Aldemir, Betül

SERAMİK TABANLI 3B DOKU İSKELELERİNİN GELİŞTİRİLİP, ÜRETİLMESİ VE KARAKTERİZASYONU ÖZET Defekte uygun doku iskelesi üretimi kişiye özel yapay kemik uygulamalarında en kritik basamağı oluşturmaktadır. Üç boyutlu (3B) yazdırma özellikle kişiye özel uygulamalarda iç ve dış tasarımın yüksek kontrol edilebilirliği ile en iyi üretim tekniklerinden biridir. Bu çalışma kapsamında kemik doku mühendisliğine iyi bir alternatif oluşturmak üzere çinko katkılı, seramik temelli (kalsiyum sülfat (KS)) doku iskelelerinin 3B yazdırma ile geliştirilip üretilmesi ve karakterizasyon testlerinin yapılması amaçl ...Daha fazlası

Yüksek Lisans 2016 Hakan OFLAZ İzmir Katip Çelebi Üniversitesi 18 Görüntülenme

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The effect of RGD pertide on cell proliferation and vasculogenesis during microtissue formation

Yaralı, Ziyşan Buse

3D (Dimensional) microtissues are commonly used in regenerative medicine, medicine design, toxicology studies and advance cancer research. Microtissues which are constructed by this technique mimic natural in vivo condition and it stands for shifting form between in vitro studies and in vivo research. Scaffold-free microtissues produce own extracellular matrix and cells proliferate faster. However microtissue is used in vitro experiments, they mimic in vivo condition by producing own matrix. Recently, RGD peptides which are commonly used biomaterials consist of GRGDS sequences and it has acti ...Daha fazlası

Yüksek Lisans 2018 Ozan KARAMAN İzmir Katip Çelebi Üniversitesi Fen Bilimleri Enstitüsü 4 Görüntülenme

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Effects of beta -tricalcium phosphate concentration on osteogenic differentiation of human mesenchymal stem cells in chitosan based composite scaffolds

Demirci, Emine Afra

Today, tissue transplant applications are widely used for repair of damaged hard tissue. Despite the gold standard of autografts, interest in synthetic bone grafts produced by tissue engineering techniques is increasing day by day, due to limiting factors such as damage to the tissue site and limited graft availability in allografts, and the risk of developing an immune system response in allografts.Many bioceramic materials, including β-tricalcium phosphate (β-TCP), hydroxyapatite (HA) and calcium sulfate, are widely used in bone tissue engineering. β-TCP has been the most preferred biocerami ...Daha fazlası

Yüksek Lisans 2018 Ozan KARAMAN İzmir Katip Çelebi Üniversitesi Fen Bilimleri Enstitüsü 11 Görüntülenme