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Evaluation of neural differentiation of PC12 cells grown on graphene coated ITO microchips Grafen kaplanmış ITO mikroçip üzerinde büyütülen PC12 hücrelerinin nöronal farklılaşmasının değerlendirilmesi

Gölcez, Tansu

ABSTRACTNervous system diseases occupy a very large place among diseases without treatment today. One of the major challenges in nervous system diseases is achieving functional connection between nerve cells. A neuronal network is a very complex structure consisting of connections between neuronal cells through dendrites and axons. In this context, a human brain can be described as a complex neuron network. Platforms capable of creating a neuronal network have the potential to be used in a variety offields, such as modeling neuron-related diseases, finding new treatments, building biological c ...Daha fazlası

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Dielectrophoretically alignment of MWCNTs in poly(ethylene glycol) dimethacrylate for neural guiding of PC12 cells PC12 hücrelerinin nöral yönlendirilmesi için ÇDKNT'lerin poli(etilen glikol) dimetakrilat içinde dielektroforetik olarak hizalanması

Seven, Fikri

ABSTRACTPC12 cell line is widely used as an in vitro model for neuronal diseases and studying cell differentiation behavior. The cell line has the ability to differentiate into neuronlike cells in the presence of nerve growth factor (NGF), resulting in neural extensions called dendrites and axons. Cell patterning is widely used in applications such as neuron network formation, tissue engineering, and cell based biosensors. In this study, the effect of randomly distributed and aligned multi walled carbon nanotubes (MWCNTs) in poly(ethylene glycol) dimethacrylate (PEGDMA) on PC12 cell neuronal d ...Daha fazlası

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Estimation of emotional situation using EEG signals and machine learning methods EEG sinyalleri ve makine öğrenme yöntemlerini kullanılarak duygusal durum kestirimi

Yeşilkaya, Bartu

ÖZETEmotion estimation is an effective analysis method used to increase the interaction between humans and machines. Electroencephalogram (EEG) based emotion prediction studies based on brain signals become very attractive since they provide successful results of emotion analysis. In this study, new methods for emotion prediction are presented in accordance with dimensional emotion modeling. Multichannel EEG signals are recorded while the subjects viewed pictures from the International Affective Image System (IAPS) data set. Signal preconditioning and artefact elimination was performed by appl ...Daha fazlası

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Evaluating steady-state visually-evoked potentials using ensemble learning methods Durağan hal görsel uyarılmış potansiyellerin topluluk öğrenmesi yöntemleriyle değerlendirilmesi

Sayılgan, Ebru

ÖZETSteady-state visual evoked potentials (SSVEPs) have been designated to be appropriate and useful for many areas in clinical neuroscience, cognitive, and in engineering. SSVEPs have become popular recently, due to their advantages such as high bit rate, simple system structure, and short training time, etc. To design SSVEP based BCI system, signal processing methods appropriate to the signal structure should be applied. One of the most appropriate signal processing methods of these non-stationary signals is the Wavelet Transform. After literature searched, we noticed that there was no study ...Daha fazlası

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Karbon elyaf takviyeli akrilik kemik çimentoları: çeşitli elektrokimyasal yüzey değişikliklerinin mekanik özelliklere etkileri üzerine bir araştırma

Emine Özge Akkaş

ÖZETPolimetilmetakrilat (PMMA) ortopedi ve travmatoloji alanında en sık kullanılanakrilik kemik çimentosudur. Protez implant ile kemik arasındaki yükün aktarılması için, eklem replasman ameliyatlarında derz dolgu malzemesi olarakgörev yapar. Bu tez çalışmasında polimetilmetakrilattan üretilen akrilik kemikçimentosuna, karbon fiber (KF) ve modifiye edilmiş karbon fiberler (KF/Zn ve KF/ZnO) eklenmiş olup, kemik çimentosunun mekanik ve termal özellikleriüzerindeki olası etkileri araştırıldı. Karbon fiberler sırasıyla elektrokimyasalkaplama ve elektrokimyasal anotlama işlemine tabi tutuldu ve karb ...Daha fazlası

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Assessment of direct and fluid mediated cold atmospheric plasma treatment efficacy on squamous cell carcinoma at three-dimensional skin culture model Direkt ve sıvı aracılı plazma muamele yöntemlerinin skuamöz hücreli karsinom üzerindeki etkinliğinin üç boyutlu deri kültür modelinde değerlendirilmesi

Özdemir, Gizem Dilara

ABSTRACTSquamous cell carcinoma (SCC) is the second most seen type of non-melanoma skin cancers after basal cell carcinoma (BCC). Prevalence of non-melanoma skin cancer increases rapidly and it’s expected to account for 50 of all cancer types in near future. It takes attention and carries importance due to higher risk of metastasis. Even though various methods are being used, those methods may either fall short or cause serious side effects. Plasma is defined as the fourth state of matter and cold atmospheric plasma (CAP) can be produced at atmospheric pressure under high electrical field. The ...Daha fazlası

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