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Effect of resveratrol on bone formation in the expanded inter-premaxillary suture: early bone changes

TANCAN UYSAL

Objective –The aim of this study was to evaluate the effects of local resveratrol (RSVL) administration on bone formation in response to expansion of the interpremaxillary suture, in rats. Material and Methods – Twenty 50- to 60-day-old male Wistar rats were separated into two equal groups. Both groups were subjected to expansion, and 30 cN of force was applied to the maxillary incisors with helical-spring. Twenty-four hours after appliance placement, single-dose 10 lmol ⁄ kg RSVL in the dimethylsulfoxide (DMSO) was injected to the inter-premaxillary suture in the experimental group. In ...Daha fazlası

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