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OPG and RANKL levels around miniscrew implants during orthodontic tooth movement

İLKNUR VELİ | ŞÜKRÜ ENHOŞ

Makale | 2013 | American Journal of Orthodontics and Dentofacial Orthopedics

Introduction: The aim of this study was to determine the peri-miniscrew implant crevicular fluid receptor activator of nuclear factor-lB ligand (RANKL) and osteoprotegerin (OPG) levels around loaded and unloaded miniscrew implants at different time intervals. Methods: Twenty loaded and 16 unloaded miniscrew implants were included in this study. All miniscrew implants were placed bilaterally between the maxillary second premolars and first molars as anchorage units for canine distalization. Peri-miniscrew implant crevicular fluid was taken from the mesiobuccal aspects of the loaded and unloaded miniscrew implants before loading; . . . at 24, 48, and 168 hours; and on day 30 after force application. Enzyme-linked immunosorbent assay kits were used to determine RANKL and OPG levels in the peri-miniscrew implant crevicular fluid samples. Wilcoxon, Mann-Whitney U, and Spearman correlation tests were used for statistical evaluations at the P\0.05 level. Results: Although the total amount of OPG was not different between the groups, the total amount of RANKL was significantly elevated in the loaded miniscrew implant group (P\0.05) at all time periods. Peri-miniscrew implant crevicular fluid volume was the highest at 48 hours in the loaded group. Also, the OPG/RANKL ratio in the peri-miniscrew implant crevicular fluid was significantly decreased in the loaded miniscrew implant group. Conclusions: The OPG and RANKL levels vary around loaded and unloaded miniscrew implants as a result of force application Daha fazlası Daha az

Dehiscence and fenestration in patients with different vertical growth patterns assessed with cone-beam computed tomography

İLKNUR VELİ | ŞÜKRÜ ENHOŞ

Makale | 2012 | The E. H. Angle Education and Research Foundation

Objective: To test the null hypothesis that the presence of alveolar defects (dehiscence and fenestration) was not different among patients with different vertical growth patterns. Materials and Methods: A total of 1872 teeth in 26 hyper-divergent (mean age: 24.4 6 4.8 years), 27 hypo-divergent (mean age: 25.1 6 4.5 years), and 25 normo-divergent (mean age: 23.6 6 4.1 years) patients with no previous orthodontic treatment were evaluated using cone-beam computed tomography. Axial and cross-sectional views were evaluated with regard to whether dehiscence and/or fenestration on buccal and lingual surfaces existed or not. For stat . . .istical analysis, the Pearson chi-square test was used at a P , .05 significance level. Results: According to the statistical analysis, the hypo-divergent group (6.56%) had lower dehiscence prevalence than the hyper-divergent (8.35%) and normo-divergent (8.18%) groups (P 5 .004). Higher prevalences of dehiscence and fenestration were found on buccal sides in all vertical growth patterns. While fenestration was a common finding for the maxillary alveolar region, dehiscence was a common finding in the mandible in all groups. Conclusion: The null hypothesis was rejected. Although the prevalence of fenestrations was not different, significant differences for dehiscences were found in patients with different vertical growth patterns Daha fazlası Daha az

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