Enhanced Anti-Cancer Photodynamic Activity with Photobiomodulation Therapy at Different Wavelengths

Büşra Sirek

Photodynamic therapy (PDT) is a non-invasive therapy that induces photochemical reactions for treating many diseases including cancer using the advantages of light. It is based on the interaction of light at a specific wavelength and light-sensitive chemical which does not have dark toxicity. Thus, PDT is an anticancer therapeutic modality yielding cancer cell death. As with other anticancer therapies, some drawbacks reduce or limit the efficacy of PDT. To eliminate the disadvantages resulting in increased efficacy of PDT, it is combined with other anticancer treatment methods. Together use of ...Daha fazlası

Yüksek Lisans 2023 NERMİN TOPALOĞLU AVŞAR İzmir Katip Çelebi Üniversitesi Fen Bilimleri Enstitüsü 23 Görüntülenme

Erişime Açık

The effect of antibacterial photodynamic therapy on healthy fibroblast and keratinocyte cells Antibakteriyel fotodinamik terapinin sağlıklı fibroblast ve keratinosit hücreleri üzerindeki etkisi

GÜLCE KADIKÖYLÜ

ABSTRACTAntibacterial photodynamic therapy is a treatment that occurs in the presence of light, photosensitizer and oxygen. The photosensitizer reacts with the molecular oxygen in the environment when it is stimulated by light at the appropriate wavelength, causing reactive oxygen species at the end. Reactive oxygen species show high cytotoxic effects on cells and cause necrosis or apoptosis. In recent years, the resistance of bacteria to antibiotics has caused infection treatments to become more difficult. This situation has become a threat to human and animal health. Therefore, antibacterial ...Daha fazlası

Yüksek Lisans 2019 NERMİN TOPALOĞLU AVŞAR Graduate School of Natural and Applied Sciences 17 Görüntülenme