Biochemical Relationship Between Glucose-6-Phosphate Dehydrogenase Deficiency and COVID-19 And Effects Of Glutathione Supplements

ABSTRACT Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose phosphate pathway involved in the production of the reduced form of nicotinamide adenine dinucleotide phosphate (NADPH). One of the most common inherited enzyme abnormalities is G6PD deficiency. G6PD enzyme deficiency facilitates human coronavirus infection due to glutathione (GSH) depletion. Depletion of glutathione due to blockage of the pentose phosphate pathway can hardly preserve the oxidative and anti-oxidative balance. GSH protects the body from the harmful effects of oxidative damage from excess reactive oxy ...Daha fazlası

Post-Earthquake Spinal Cord Injury: Role of Physiotherapy and Rehabilitation

TURHAN KAHRAMAN

This review examines the crucial role of physiotherapy and rehabilitation in the management of post-earthquake spinal cord injuries (SCI). After an earthquake, patients with SCI require specialized and intensive rehabilitation programs to promote recovery, prevent complications, and enhance their quality of life. This article reviews the pathophysiology of post-earthquake SCI, the various clinical and functional assessments used to evaluate severity, and the different treatment options available including pharmacotherapy, surgical interventions, and rehabilitation. This review discusses the ch ...Daha fazlası