The effect of RGD pertide on cell proliferation and vasculogenesis during microtissue formation

Yaralı, Ziyşan Buse

3D (Dimensional) microtissues are commonly used in regenerative medicine, medicine design, toxicology studies and advance cancer research. Microtissues which are constructed by this technique mimic natural in vivo condition and it stands for shifting form between in vitro studies and in vivo research. Scaffold-free microtissues produce own extracellular matrix and cells proliferate faster. However microtissue is used in vitro experiments, they mimic in vivo condition by producing own matrix. Recently, RGD peptides which are commonly used biomaterials consist of GRGDS sequences and it has acti ...Daha fazlası

Yüksek Lisans 2018 Ozan KARAMAN İzmir Katip Çelebi Üniversitesi Fen Bilimleri Enstitüsü 7 Görüntülenme

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Effects of beta -tricalcium phosphate concentration on osteogenic differentiation of human mesenchymal stem cells in chitosan based composite scaffolds

Demirci, Emine Afra

Today, tissue transplant applications are widely used for repair of damaged hard tissue. Despite the gold standard of autografts, interest in synthetic bone grafts produced by tissue engineering techniques is increasing day by day, due to limiting factors such as damage to the tissue site and limited graft availability in allografts, and the risk of developing an immune system response in allografts.Many bioceramic materials, including β-tricalcium phosphate (β-TCP), hydroxyapatite (HA) and calcium sulfate, are widely used in bone tissue engineering. β-TCP has been the most preferred biocerami ...Daha fazlası

Yüksek Lisans 2018 Ozan KARAMAN İzmir Katip Çelebi Üniversitesi Fen Bilimleri Enstitüsü 18 Görüntülenme