3D (Dimensional) microtissues are commonly used in regenerative medicine, medicine design, toxicology studies and advance cancer research. Microtissues which are constructed by this technique mimic natural in vivo condition and it stands for shifting form between in vitro studies and in vivo research. Scaffold-free microtissues produce own extracellular matrix and cells proliferate faster. However microtissue is used in vitro experiments, they mimic in vivo condition by producing own matrix.
Recently, RGD peptides which are commonly used biomaterials consist of GRGDS sequences and it has acti ...Daha fazlası
This thesis focuses on a Multileaf Collimator design that can shape the beam contour to fit the shape of target geometry and its design improvements. Main purpose of this design is lowering the number of leaves on the multileaf collimator and making the system easier to be controlled. As the Collimator devices undertake the most important point of the beam shaping procedure, ease of control and precision of collimator devices are the major points of operation.
As the radiation therapy is one of the most complex and vital medical operations, this thesis started with the deep literature survey ...Daha fazlası
Graphene, a one-atom-thick two-dimensional material, has drawn great interest for many electronic and optoelectronic applications due to its extraordinary properties. The properties of the graphene can be modified with different chemical methods and introduced new properties, which widens its potential for applications. The non-covalent modification of graphene is one of the basic techniques for modifying the electrical properties of graphene without disrupting the structure.
In this thesis, the high-quality graphene has been synthesized and electrical properties of graphene have been tuned b ...Daha fazlası
In this study, the necessary data obtained from the databases (such as MSSQL, Mysql, Postgre SQL, etc.) of the softwares like ETA and NETSİS that are used for preaccountancy of the local and global companies were read, some of the data were written to the databases, and this data was used by the end user by using mobile phones or tablets carrying Android operating systems and working with Internet and cloud technology. In addition, new data sets that are collected on a cloud system from the accounting data while the company is on was studied by genetic algorithms which are one of the artificia ...Daha fazlası
Within the scope of the thesis study, interpolation methods used for evaluating spatially varying data and for presenting the information obtained from the data via maps were investigated. A method for generating an open source web based interpolation map for the most commonly used interpolation methods is presented. Today, many commercial Geographic Information Systems (GIS) software are used in the production of interpolation maps. However, this situation causes the users to pay a large amount of money or use cracked programs. Although there are open source softwares, which can create interp ...Daha fazlası
The goal of this study is developing custom designed optical tweezer which uses two
He-Ne lasers (λ=632.8 nm) parallel to each other to trap yeast cells. The
characteristic specs of this optical tweezer determined by Brownian Motion of
polystyrene beads in water. Stiffness and trapping forces of optical tweezer
calculated for laser 1, laser 2 and when both lasers used simultaneously. Laser 2 can
trap and move particle to laser 1 and multiple particles can be trapped by the laser 1.
After determination of specs of optical tweezer, yeast cells in yogurt culture medium
were trapped by lase ...Daha fazlası
ABSTRACTBulletproof composite armor models are investigated using finite element software ANSYS/AUTODYN. A composite plate is modelled with Kevlar 29/epoxy, analysed, and the results obtained by this model are confirmed with the results available in the literature. Different materials are tested as secondary materials in the composite plate. The results obtained by these materials for unit weight and for residual velocities of the projectile are compared. A new stacking sequence study is conducted with the Kevlar 29/epoxy as primary material and Ultra High Molecular Weight Polyethylene (UHMWPE ...Daha fazlası
ABSTRACTIn the last century, the energy demand of the world has been continuously increasing, and new and more environment-friendly energy sources search continues.As a result, Solar Cells have emerged as a renewable energy type. With the fact that when the sun is used efficiently it is a constant source of energy and a never-ending source of energy all over the world, triggering scientific studies on this subject and intensifying studies on solar batteries.With the influence of the economic factors in the materials, this issue has come up in three phases day by day. The fact that it is cheap, ...Daha fazlası
ABSTRACTSevere Plastic Deformation (SPD), applying extreme force to alterate and refine the structures of materials permanently, have a huge potential to improve the mechanical and structural properties of materials superiously. ECAP is a kind of SPD techniques to produce submicron or nano sized grains in the material structure by applying stress to the sample passing through two angular intersected channels have the same diameters. ECAP has recently been becoming one of the most favourable candidate method in the production of nanostructured materials.One of the main objectives of this study ...Daha fazlası
ABSTRACTIt is not possible to produce steel without inclusions as the process for steel production requires. Based on this fact, the researches on clean steel are concentrated on the reduction of inclusions and transformation of inclusions into harmless state by modification. The definition of steel cleanness is related to final product application. Non-metallic inclusion, in the liquid steel, causing many problems and production lost in steel production process and final application. Aluminum killed steels mostly contain Al2O3 and MnS inclusions. Al2O3 inclusions are formed during de-oxidatio ...Daha fazlası
ABSTRACTDiabetes Mellitus (DM) is a chronic disease that progresses rapidly. Today, thenumber of diabetic patients is increasing day by day, but treatment methods arebeginning to be inadequate due to the insufficient time, financial deficiencies andother restrictions. Diabetes education and treatment are very important for thediabetic to survive. Diabetes treatment is practiced in many areas of life from thenutrition habits to the social life activities. In terms of the course of diabetestreatment, it is necessary for the self-management of the patient to follow thediabetes education and appli ...Daha fazlası
ABSTRACTCities that have a history as a capital or an important trade center, has its own complex structure. If the historical city center was functionalized as a commercial district, it has been experienced social, cultural, environmental and economical subjects throughout centuries. This situation creates strong impacts as newly created contexts likewise political, public and architectural. These contexts generally not thought together, but they should be analyzed and investigated together for a sustainable future for the historical city centers. As a historical city center, Kemeralti-Izmir ...Daha fazlası
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.