Dielectrophoretically alignment of MWCNTs in poly(ethylene glycol) dimethacrylate for neural guiding of PC12 cells PC12 hücrelerinin nöral yönlendirilmesi için ÇDKNT'lerin poli(etilen glikol) dimetakrilat içinde dielektroforetik olarak hizalanması

Seven, Fikri

ABSTRACTPC12 cell line is widely used as an in vitro model for neuronal diseases and studying cell differentiation behavior. The cell line has the ability to differentiate into neuronlike cells in the presence of nerve growth factor (NGF), resulting in neural extensions called dendrites and axons. Cell patterning is widely used in applications such as neuron network formation, tissue engineering, and cell based biosensors. In this study, the effect of randomly distributed and aligned multi walled carbon nanotubes (MWCNTs) in poly(ethylene glycol) dimethacrylate (PEGDMA) on PC12 cell neuronal d ...Daha fazlası

Yüksek Lisans 2020 Mustafa Şen Graduate School of Natural and Applied Sciences 26 Görüntülenme

Erişime Açık

Evaluation of neural differentiation of PC12 cells grown on graphene coated ITO microchips Grafen kaplanmış ITO mikroçip üzerinde büyütülen PC12 hücrelerinin nöronal farklılaşmasının değerlendirilmesi

Gölcez, Tansu

ABSTRACTNervous system diseases occupy a very large place among diseases without treatment today. One of the major challenges in nervous system diseases is achieving functional connection between nerve cells. A neuronal network is a very complex structure consisting of connections between neuronal cells through dendrites and axons. In this context, a human brain can be described as a complex neuron network. Platforms capable of creating a neuronal network have the potential to be used in a variety offields, such as modeling neuron-related diseases, finding new treatments, building biological c ...Daha fazlası

Yüksek Lisans 2020 Mustafa Şen Graduate School of Natural and Applied Sciences 36 Görüntülenme

Erişime Açık

Using screen-printed electrodes modified with carbon based nanomaterials for sensitive detection of biologically relevant molecules Biyolojik olarak önemli moleküllerin duyarlı tespiti için karbon bazlı nanomalzemeler ile modifiyeedilmiş ekran baskılı elektrotların kullanılması

Azizi, Ehsan

ABSTRACTBiologically relevant molecules such as glucose, hydrogen peroxide, and dopamine are important for human body and directly affect some bodily functions. Sensitive measurement of these molecules enables humans to prevent some serious problems arising from abnormal levels of these molecules. In this thesis, glucose and dopamine were measured using screen-printed electrodes (SPE) modified with various types ofcarbon-based nanomaterials. The SPEs used here are commercially availableelectrodes in which all the necessary components (working, counter and reference electrodes) for the measurem ...Daha fazlası

Yüksek Lisans 2022 Mustafa Şen Graduate School of Natural and Applied Sciences 37 Görüntülenme