The effect of RGD pertide on cell proliferation and vasculogenesis during microtissue formation

Yaralı, Ziyşan Buse

3D (Dimensional) microtissues are commonly used in regenerative medicine, medicine design, toxicology studies and advance cancer research. Microtissues which are constructed by this technique mimic natural in vivo condition and it stands for shifting form between in vitro studies and in vivo research. Scaffold-free microtissues produce own extracellular matrix and cells proliferate faster. However microtissue is used in vitro experiments, they mimic in vivo condition by producing own matrix. Recently, RGD peptides which are commonly used biomaterials consist of GRGDS sequences and it has acti ...Daha fazlası

Modeling and experimental study of turbulent newtonian fluid in fully eccentric annulus considering temperature and pipe rotation effects

In this work, the effect of temperature on the pressure loss of Newtonian fluid in a fully eccentric annulus with pipe rotation is investigated. For this purpose, initially comprehensive experimental study has been conducted at Izmir Katip Celebi University (IKCU), Fluid Mechanics and Hydraulics Laboratory of Civil Engineering Department. Effect of temperature has been observed for flow velocities from 0.7 m/s to 3.4 m/s, for pipe rotations from 0 rpm to 120 rpm, and for temperatures is from 20 °C to 65 °C. The pressure loss within the test section is recorded. An increase in the liquid temper ...Daha fazlası

Nanocomposites with graphene

The carbon fiber used in the manufacturing of advanced composites has various applications in the automotive, aerospace, and electronics industry because of their comprehensive properties such as lightweight, flexibility, high strength to weight ratio, excellent chemical resistance, superior electrical conductivity and thermal conductivity. Different kinds of carbon fiber precursors have been used and polyacrylonitrile (PAN) is the mostly utilized polymer type which is a petroleum-based, expensive and unsustainable. Remarkably, lignin is a highly accessible, low-cost, and renewable resource. ...Daha fazlası

Design and development of a collimator mechanism that will be utilized in radiation therapy

Yazıcı, Mustafa Volkan

This thesis focuses on a Multileaf Collimator design that can shape the beam contour to fit the shape of target geometry and its design improvements. Main purpose of this design is lowering the number of leaves on the multileaf collimator and making the system easier to be controlled. As the Collimator devices undertake the most important point of the beam shaping procedure, ease of control and precision of collimator devices are the major points of operation. As the radiation therapy is one of the most complex and vital medical operations, this thesis started with the deep literature survey ...Daha fazlası

A visiual isarithmic mapping tool for online maps

Atalay, Hatice

Within the scope of the thesis study, interpolation methods used for evaluating spatially varying data and for presenting the information obtained from the data via maps were investigated. A method for generating an open source web based interpolation map for the most commonly used interpolation methods is presented. Today, many commercial Geographic Information Systems (GIS) software are used in the production of interpolation maps. However, this situation causes the users to pay a large amount of money or use cracked programs. Although there are open source softwares, which can create interp ...Daha fazlası

Development of microstructural and mechanical properties of aluminum alloys by equal channel angular pressing (ECAP) process Eş kanal açılı presleme (EKAP) yöntemiyle aluminyum alaşımlarının mikroyapı ve mekanik özelliklerinin geliştirilmesi

Yeşil, Mehmet Mahsun

ABSTRACTSevere Plastic Deformation (SPD), applying extreme force to alterate and refine the structures of materials permanently, have a huge potential to improve the mechanical and structural properties of materials superiously. ECAP is a kind of SPD techniques to produce submicron or nano sized grains in the material structure by applying stress to the sample passing through two angular intersected channels have the same diameters. ECAP has recently been becoming one of the most favourable candidate method in the production of nanostructured materials.One of the main objectives of this study ...Daha fazlası

Smart business accounting software as an android mobile application using artificial imtelligence

Okyay, Muhammet Serhat

In this study, the necessary data obtained from the databases (such as MSSQL, Mysql, Postgre SQL, etc.) of the softwares like ETA and NETSİS that are used for preaccountancy of the local and global companies were read, some of the data were written to the databases, and this data was used by the end user by using mobile phones or tablets carrying Android operating systems and working with Internet and cloud technology. In addition, new data sets that are collected on a cloud system from the accounting data while the company is on was studied by genetic algorithms which are one of the artificia ...Daha fazlası

Finite element analysis of material and parameter effects in ballistic armors Balistik zırhlarda malzeme ve parametre etkilerinin sonlu elemanlar yöntemiyle analizi

Latif Tibet Aktaş

ABSTRACTBulletproof composite armor models are investigated using finite element software ANSYS/AUTODYN. A composite plate is modelled with Kevlar 29/epoxy, analysed, and the results obtained by this model are confirmed with the results available in the literature. Different materials are tested as secondary materials in the composite plate. The results obtained by these materials for unit weight and for residual velocities of the projectile are compared. A new stacking sequence study is conducted with the Kevlar 29/epoxy as primary material and Ultra High Molecular Weight Polyethylene (UHMWPE ...Daha fazlası

Incubator monitoring system for newborn infants using Raspberry PI Raspberry pi kullanılarak bebek kuvözü izleme sistemi geliştirilmesi

Selek, Mehmet Hakan

ABSTRACTPreterm newborns are unlikely to live without any additional support. Babies born in this way need special care and a place that would imitate their mother’s womb as much as possible. The environmental conditions like the temperature, humidity, noise, light intensity, etc. need to be carefully managed. In addition to managing the environment, it is necessary to record vital data such as baby's temperature and pulse and record any changes so that they can be examined later. Since the systems that carry out these mentioned controls are very expensive, there are still hospitals that do no ...Daha fazlası

Neurovascular Co-Cultures in hydrogel building blocks Hidrojel bloklarda nörovasküler ko-kültür çalışmaları

Ersoy, Fulya

ABSTRACTCreating a tissue or an organ model is the most emerging field of the biomedical research for the last decades. Three-dimensional scaffolds that will mimic the extracellular matrix were designed and used in various applications to investigate the behavior of cells.In this study, both the synthesis of the polymer and the fabrication of three-dimensional hydrogel scaffolds were practiced. Gelatin methacrylate (GelMA) was synthesized prior to photopolymerization of the hydrogel. A novel scaffold fabrication device was designed and manufactured. This device allowed us fabricating computer ...Daha fazlası

Increasing the efficiency of dye-sensitized solar cells using ionic liquid based electrolytes Boya duyarlılaştırılmış güneş pillerinin verimlerini iyonik sıvı esaslı elektrolitler kullanarak artırmak

Mustafa Yaşar

ABSTRACTIn the last century, the energy demand of the world has been continuously increasing, and new and more environment-friendly energy sources search continues.As a result, Solar Cells have emerged as a renewable energy type. With the fact that when the sun is used efficiently it is a constant source of energy and a never-ending source of energy all over the world, triggering scientific studies on this subject and intensifying studies on solar batteries.With the influence of the economic factors in the materials, this issue has come up in three phases day by day. The fact that it is cheap, ...Daha fazlası

Manufacturing and characterization of thermal conductive polymeric composite materials Termal iletken polimerik kompozit malzemelerin üretilmesi ve karekterizasyonu

Kaya, Nusret

ABSTRACTElectronic industry is growing dramatically in the last quarter of the century. Recent advances in electronics industry enable the miniaturization of micro transistors and the integration of more transistors into the electronic devices, resulting in a higher performance device. However, this condition increases the heat flow in the electronic devices. The performance of electronic devices depend on the working temperature, for this reason, it is important to remove the heat produced in the device as fast and efficiently as possible in order to hold the system temperature of the electro ...Daha fazlası